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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'befda5e1827e7d954dc800a5d8801379a858dcd8505d644b607c6e7319e09e2f' 
  AND token = 'G0+5JbY8UVJyaS6uOhpa/OIDR8rtaKR9cKKQy35wyRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}