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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '498599b52cc2b64b67eea951516a134ff594e1052dfff7f3ab43dc35987a7b76' 
  AND token = 'KxQ+Q8rs50j1d9Ydtsc0Tx53Lw7QI6wysdHT9EUPv6s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}