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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecb591df6be186bb13bc98fb4f7ece009119f26e16199d05eac3f4b31a03121a' 
  AND token = 'cfPzVhp0uINl7N+U2rMhPIUmtTkfMQvZfQ7zHM/2rY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}