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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e010857a5afc0b42800c72f15a40a38665ad44dbc485b5b6b55b171db29877f' 
  AND token = 'w2MZxYgzdOE3wt6bfwY8k9zCzb+rzBD1LXSgekrorrM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}