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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b78476ea5a13b2c8e8e89a751202f0b6487028bdd5ad6ca212af8ea86c85813' 
  AND token = 'DMe8aIqZyy5mHomrRbs+B5LMo1c4weCER0GLHAer4eU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}