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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e63a474d7f089b6f5b1a34bc03ee380643176f72a96d85a42fcb8ff39161f665' 
  AND token = 'rFG3PrdRvhJcSeDzTJk+Df5X1o7aP112aSgLn2qswWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}