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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '541b54c0b2b22efd300674df29b915c6839278d3aef1bc3ad68b370e499661fc' 
  AND token = 'R8v+VEgKt+Rd9aom0SqSm+AvCitdsAHdmVOseLhC+n8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}