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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '637a762b5aca28000283cff1206fe8e37140f94ed5d6ea9a1635f200bd5d1c14' 
  AND token = 'qC47PicnbUY/TtOIT27w44a0Pxz0LANuW4ekZaT3RA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}