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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24e3bb80f0fbcd0749e5c5e08b248a1211ada424db477a72e68dc1d54d2b7fcf' 
  AND token = 'AibxV1zlSRtmfGfmQ82+2+2wpe/OYZgTf8p1YaUAJbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}