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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a35d273d2df3d3d87ba8b40349f913d6ab46415104e74c90592828dd3e6c0f10' 
  AND token = 'n9z+ANDI8hrqYjt5nHpp+jjPZuTyEuPZ+U2ATml9tI8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}