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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7c975b29d6340a83bf5073f72a8ae02841e8e74802edfd94939924bf03e45b3' 
  AND token = 'oRUGoWyfa4nqW+SR6uQRhu8OuTVHRZqzLkRRKybpgCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}