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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27cc2190507f2059dfe20001b3603dc48947ee1eb85b9d559119d0eac4953575' 
  AND token = 'UKRAMD05S5UZuvCW90ZjaXX48ahg1QvhBKGMZyL8do0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}