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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6638b810d3b6728e9bfe0a4ee4582b48a2c51c8ffe1130c1964dff6d5d9bb6b' 
  AND token = 'eQwjP06JKz5z7d7jrz0ycO2ABvkZ2unX8QUxBr0cvCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}