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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee5e59dd02a4af528707b0da457868136843da0c7ade0416851411c464de8e39' 
  AND token = 'b9d13c/A2+++zjD4vxq4i5ZF2TM2Q9KMwkQfa21bwCo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}