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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78f5d4e83a4fa2432e5254afbca22fa8f57335839f974de0282817f6ea8292b9' 
  AND token = 'dZyKrV/PeErkp35pj4iAjNYNg0v39+Z4X8scYRjD+l8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}