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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c7142f2fb603e6f81aab08fe8d01beeec766f4137491a98048fc44013680b0c' 
  AND token = 'b3qJtloAAEzjict7xHTMRXqLK53m1G09llK/TT5t+0U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}