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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '406681620172f231e6192f16319e86e37a90ee59b4988b5849763ab00a0a5e7f' 
  AND token = '1KOb10P9MvDChWlMxWQReorgFq6kNVu5a5H0LxkdfwE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}