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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a95d8c9133647abbe89946362b768d9d7801b76f0e65b51df88038d7016b880' 
  AND token = 'eCfP6xUMd2rQlKSkllBAr0RMf8m4ifsqF2XBmk0m8dQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}