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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12120021725e5c3d5696c102a2d84e12012122af726d72aa06bcb7c9b208c947' 
  AND token = 'ICAtEJAuao+E+NI0OrDNKx+02kmiGzY08xk9vHat89o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}