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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8227525cf55b2969e6be0af4d90b39fd4134f8f07ece27fb437d816155d78ee6' 
  AND token = '0Kd+5pvSQkBuapOva/1rZb9VNMZQjQzMHskoMs2vWDk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}