SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e51dcdc35f702f4c80a137eda64fc1f4bed293d543aa0458d5357e77e1839e7f' 
  AND token = 'SrOV/hkNthJkxMU9rvgpjJGx6EmX5Vgxo8rX7hqekdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}