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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b6dd18457f7eaa41be115fa28922a5420d7f573c0e7ca51da6419a6b6cb68ff' 
  AND token = 'koIFk3SaOFnzzWxMN8bHiOEsv7dEXwdQqWNduqt9OQw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}