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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '97aa80d920e4a8e84dfdf26b824a444d86e15aa84e9f2acd42fc2eb528a014a5' 
  AND token = '5eR+dXw0kWLYAFpI/WrvyIG4+MV+bmQJ1gMDsnI/ggA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}