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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d774b78a9d6b307d13bae13c8aac7f6fe99f8f896f1acc9ff4f56f53005e8a5' 
  AND token = 'bRgrHfwYcG29KjgbVVaEoc5A8o7aA7u9AlGPqYTFkqU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}