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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '403b2ea3a0717512c3ad57286fbd1d6e8f2057dce310ecfe42d1e059fc78a473' 
  AND token = 'qtwMIZ59jR6dKxjmwFRvKMU8uKFD51VyoC7C5s2A3ZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}