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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '430f1c97606a64df29b831b1d8cf57324ca377747ee67e86d9d15d47eb60983b' 
  AND token = 'KInC8nfxsh/a5UaXhUjPwOoL0fWwXtXynQsDiSOYlCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}