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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65798561ef4a07a1203838676935da2e49402e84d02e671273ae4d0ef0fd8839' 
  AND token = 'HVi1DHmA2RQhsRl2QZBSCk0MZVuAdKWyi8v28zZtrwQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}