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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3378e0e7806057b16835b19ee3f88296f5d410bfc5aa4d8cbe0f0bd02c3db041' 
  AND token = 'Hjc1qnLQE29CGXrIX+0unpnpVRnOt64a0XqA3b/J9hw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}