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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dda0e7034a686156f8cd66de70fddb24191293b6ce9c121a729f37f823f5c8f3' 
  AND token = '4JZA+HtSWa4mXtWHXXgwIwAT7eNjMCLZHyFnZ0CgSe8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}