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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6672787bdda11794de431838f39ba3abfe19129ef40a203c4d0045680cc189f' 
  AND token = 'KPN2Wk1By0/KISpFoW0ATOEfgRP9M0kzFwtCfKSu+T0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}