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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72dbd79c980c42c5e2ea54859de76cca8b2dfe1bff8354a6301ff82c0573691e' 
  AND token = 'KIV3ESa94OrnmVGzDShFpIs+/uqo4fOtlIttWMtRyYs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}