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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27f8cc67c2f7ecb6998d0de96fdff187ef8ca452a18b782cf9a79829549c2d56' 
  AND token = 'tbh63yJ9u/iLY6XAMkTT4VzyUYIysgnFJ2Q13kd3X0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}