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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3376c7470d07b8e9d2e1b2423cb2e516db7cf356d7615eff2ee16d6836434333' 
  AND token = '5169KaKQ/B3k4nFRxyB032dxr/CF/ApVimGtc4jVwOo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}