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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53b836a775e2b2ac00832d929469a953d8bb1ca1d1fa091dd045da887f2d5b3e' 
  AND token = 'wG4+NAterWVjdc7pjTKLUZq9RfCv25jmsrj+jz9LCE4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}