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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '174c819cf980eb0a28471d7460054e344c2dab4613a92cdd82a613ff525ff83c' 
  AND token = 'R9qf8Qdri3Ya/+btsji8E7MSmn2TOQIcxwHgRoV2JT8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}