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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0f147d7a2f4759db299c5c5be2ee96bf97736a55f85b09bb55166770d5ef0f4' 
  AND token = 'NvEQpGjQyVOG8c1lqoqPeYGv9E+QMbBF9u7rhv2d6yc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}