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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bdd34524f91aa8c32e5f47ed378fa49c2a0c5f723d64ea76e58580a4501515a' 
  AND token = 'ZS+0rb1O70L4Yw7UboGDQRCvAZMhUXAYJVNfNc9HltM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}