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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2312342a0da3fc65bb86470bfd72aa70f2234442e723cf1a039de0b4b7d7d49e' 
  AND token = 'b+6mc/zoCNSH/XwQSm40KkUCyebvG0ZA0+6oBo2DAow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}