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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95e715464f5988b1297485888a7545a28c1dfd54dcf0e777da1d9608cd97ee45' 
  AND token = 'lZ1P8DIx/3Y3DqOEg/uELRXPZ4uk2nG9PRq+gg0UTec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}