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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b2fb3aa47a390d89a026945db545557f05b5bfda89acfe43fda159c4da91512' 
  AND token = '0VO/A9onQL7a/h0bkHE820u+OSx7GFn1eDvFE225eQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}