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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c60031ebedf0d83c4f7cba967f64eeb061f5d0a9d2cc21654a020e5cda61d5b' 
  AND token = 'eEIz3+jBTVaIWDAvnsZkrqRxzR1IyngjEc2gu/V+JTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}