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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16ecea67cac3b1d161943aa2e1115023420e41e7557ad2babc794479f6f8f8c1' 
  AND token = 'a7pv6RHPdYR+QN7dpxcM3VtC/nD9ffxmhg61dnYk1bY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}