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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7717e0299e602324dd8a542be479906b2c59ffb7b377981b0c473b12682b7e08' 
  AND token = 'W05/ToDJ4pe90Ci1uBXuJ5dEV2GlDrImu9jDUWy3Fgk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}