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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ad435a50d7340d7b3ede270875841dca8890c152c18eb528650bfe9ce2949de' 
  AND token = 'slMVqprtb0/HwKwVB4pES1Po+DYV3Pun2CeK7RX5OS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}