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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fb0c35acaf4762b30da04eedfe1440e256fdbc520293d0345bcba2ed7b09a4d' 
  AND token = 'fJAbD7MZ0Ic3VXsJn3rrDFykP+jYiQ7kjyaCtFFzhIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}