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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a696c69bd1576b39cdda759758088a51bad73e254f3ca5fe4f8b0e1507f64e53' 
  AND token = 'R5q5MMVTAa86ak0X+sDcoguYoPdIxLLYiptQ3ymEW6E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}