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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdb36462959999b692e71b5c1856e3040c1add8963c8d02e8f5b79cd2109e493' 
  AND token = 'zjkFNNNXV5imlRV8gt4SxKkinhFyXTTufb4Z+VZFlZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}