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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e79dbe234d2e6cfb45566d132bb01332b4b2e65f87434fc1b854b04c6d54dec4' 
  AND token = '/KkBZuFHQq5mhewegArTedbXOWhFxXyIB/jZl6WFMwU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}