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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6d9cc4a46b11ecead3a523235b39d46acc2e6a7b9673264a59137b02cd3bd3f' 
  AND token = 'tXVQh+MwDxkex3fSFtHru+KwuGjZKzMEZ0BQmslYifc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}