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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38b0e1c4d84b1600431f3acb35f0b8717a93deee5615053f3c52db25f21b54b3' 
  AND token = '6zxXaCCNbqQz0GGmPBu4INhz+JLjVtEj2f2B9AU1nSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}